Ischemic Stroke

Ischemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism. Ischemia is generally caused by problems with blood vessels, with resultant damage to or dysfunction of tissue. It also means local anemia in a given part of a body sometimes resulting from constriction. Ischemia comprises not only insufficiency of oxygen, but also reduced availability of nutrients and inadequate removal of metabolic wastes. Ischemia can be partial or total.

Brain ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. This leads to poor oxygen supply or cerebral hypoxia and thus leads to the death of brain tissue or cerebral infarction / ischemic stroke. It is a sub-type of stroke along with subarachnoid hemorrhage and intracerebral hemorrhage.

Ischemia leads to alterations in brain metabolism, reduction in metabolic rates, and energy crisis.

There are two types of ischemia: focal ischemia, which is confined to a specific region of the brain; and global ischemia, which encompasses wide areas of brain tissue.

Symptoms of Brain ischemia

The main symptoms of Brain ischemia involve impairments in vision, body movement, and speaking. The causes of brain ischemia vary from sickle cell anemia to congenital heart defects. Symptoms of brain ischemia can include unconsciousness, blindness, problems with coordination, and weakness in the body. Other effects that may result from brain ischemia are stroke, cardiorespiratory arrest, and irreversible brain damage.

There two main types of ischemic stroke.

• Cerebral thrombosis

• Cerebral embolism

Causes ischemic stroke

• Ischemic stroke occurs when an artery that supplies blood to the brain is blocked by a blood clot or fatty buildup, called plaque. This blockage can appear at the neck or in the skull.
• Clots usually start in the heart and travel through the circulatory system. A clot can break up on its own or become lodged in an artery. When it blocks a brain artery, the brain doesn’t get enough blood or oxygen, and cells start to die.
• Ischemic stroke caused by a fatty buildup happens when plaque breaks off from an artery and travels to the brain. Plaque can also build up in the arteries that supply blood to the brain and narrow those arteries enough to cause ischemic stroke.
• Ischemic stroke occurs when an artery that supplies blood to the brain is blocked by a blood clot or fatty buildup, called plaque. This blockage can appear at the neck or in the skull.

Submit manuscript via online  https://www.imedpub.com/submissions/stroke-research-therapy.html or email us at manuscripts@imedpub.com

Regards               

Meria Den          

Managing Editor              

Stroke Research & Therapy